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CAS 53714-56-0 Leuprorelin Raw Material For Medicine Manufacturing C59H84N16O12

Basic Information
Place of Origin: CHINA
Brand Name: MOSINTER
Certification: COA
Model Number: Antineoplastic Drugs API - 36
Minimum Order Quantity: 1KG
Price: Negotiation
Packaging Details: Aluminum foil bag, fiber can, kraft paper bag
Delivery Time: Within 7 days
Supply Ability: Can be customized according to customer requirements
Detail Information
Name: Leuprorelin CAS: 53714-56-0
Appearance: Powder Molecular Formula: C59H84N16O12
Molecular Weight: 1209.4 Purity: 99%
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chemical raw materials

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pharmaceutical raw materials


Product Description

Leuprorelin CAS 53714-56-0 Pharmaceutical Grade Chemicals
 
Description:

 

Several drugs commonly used in clinic to remove ovaries for the treatment of premenopausal breast cancer and prostate cancer


Specifications:

 

ITEMS SPECIFICATION RESULT
Appearance White powder Conforms
Solubility

Soluble in water or 1% acetic acid at a

concentration of ≥1mg/ml to give a clear,

colorless solution

Conforms
Identity

A. IR

Same with the reference spectrum of Leuprolide

B. HPLC

Same with the reference solution

C. Amino Acid Analysis

Ser: Present

Glu: 0.85~1.1

Pro: 0.85~1.1

Leu: 1.80~2.2

Tyr: 0.85~1.1

His: 0.85~1.1

Arg: 0.85~1.1

Trp: Present

 

Conforms

 

Conforms

 

 

0.84

0.97

1.04

2.02

1.01

0.99

1.00

present

Specific Optical Rotation -38.0~-42.0° [a]20D(c=1,1% HAc) -39.2°

RelatedSubstance

(By HPLC)

Total Impurities(%)≤2.5%

acetyl-leuprolide≤1.0%

D-His-leuprolide≤0.5%

L-Leu6-leuprolide≤0.5%

D-Ser-leuprolide≤0.5%

Any other Impurity≤0.5%

0.21%

Conforms

Conforms

Conforms

Conforms

0.2%

Acetate Content(By HPLC) 4.7~9.0% 8.7%
Water Content(Karl Fischer) ≤5.0% 1.4%
Sulphate ash ≤0.3% Conforms
Bacterial Endotoxins ≤16.7 IU/mg Conforms
Residual Organic Solvents

Acetonitrile ≤0.041%(By GC)

DMF ≤0.088%(By GC)

MEOH ≤0.3%(By GC)

TFA ≤0.1%(By HPLC)

Conforms

Conforms

Conforms

Conforms

Assay(By Anhydrous, Acetic Acid-free ) 97.0~103.0% 98.10%

 

Application:

 

To improve the serum concentration of testosterone and dihydrotestosterone, so as to achieve the function of treating reproductive system diseases. For the treatment of prostate cancer, hysteromyoma, ovarian cyst, breast cancer and cryptorchidism in children.

 

Our strengths:
 
We can customize according to customer's requirement.
If you have any question pls mail us or call us.

 

Contact Details
Fedor

Phone Number : +86 18989305995

WhatsApp : +18989305995