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Cefazolin CAS 25953-19-9 C14H14N8O4S3 Pharmaceutical Grade Chemicals

Basic Information
Place of Origin: CHINA
Brand Name: MOSINTER
Certification: COA
Model Number: Antibiotic Drugs API - 44
Minimum Order Quantity: 1KG
Price: Negotiation
Packaging Details: Aluminum foil bag , kraft paper bag
Delivery Time: Within 7 days
Payment Terms: L/C, T/T
Supply Ability: Can be customized according to customer requirements
Detail Information
Name: Cefazolin CAS: 25953-19-9
Form: Powder Molecular Formula: C14H14N8O4S3
Molecular Weight: 454.51 Melting Point: 198-200 ℃
High Light:

chemical raw materials

,

raw material for medicine manufacturing


Product Description

Cefazolin CAS 25953-19-9 C14H14N8O4S3 Pharmaceutical Grade Chemicals​
 
Description:
 

Cefazolin (INN), also known as cefazoline or cephazolin is an antibiotic useful for the treatment of a number of bacterial infections.

It is a first-generation cephalosporin antibiotic. Cephalosporins fall into the category of β-Lactam (beta-lactam) antibiotics. Other antibiotics that fall into this category are penicillin derivatives, monobactams and carbapenems. This group of antibiotics works by inhibiting cell wall synthesis of the bacteria by binding to penicillin-binding proteins. These groups of antibiotics are known as bactericidal, meaning that they kill the targeted bacteria (as opposed to inhibiting reproduction as bacteriostatic antibiotics do).

 
Specifications:

 

Test

Specification

Result

Result

CHARACTERS

White or almost white Powder

White powder

Complies

IDENTIFICATION

Complies

Complies

Complies

Appearance of Solution

430nm ,≤0.15

0.029

Complies

PH

4.0 -6.0

5.6

Complies

Specific Optical Rotation

-15°- -24°

-21°

Complies

Absorbance

260-300

277

Complies

Related Substance

Impurity (individual )≤1.0%

0.19%

Complies

Impurity (total )≤3.5%

1.0%

Complies

N.N –Dimethylantine

≤20ppm

<20ppm

Complies

Water

≤6.0%

0.9%

Complies

Sterility

Complies

Complies

Complies

Bacterial endotoxins

≤0.15IU/mg

Complies

Complies

Assay (Calculated as anhydrous substance )

950%-102%

99.3%

Complies

Conclusion

Complies with EP6th Standard

 

Application: 


 This product is the semi-synthetic first generation cephalosporin, the antibacterial effect and cefalotin, cefosporin basically the same.Gram-positive bacteria such as staphylococcus aureus, hemolytic streptococcus, pneumococcus, diphtheria bacteria and clostridium bacteria have a strong role.The effect on gram-negative bacteria was also stronger, especially on klebsiella pneumoniae.It is also effective against e. coli, proteus strangis and typhoid.But not for pseudomonas aeruginosa.This product has obvious superiority in the first generation cephalosporin.It is characterized by enzyme resistance, high efficiency and low toxicity. It is generally effective for gram-positive and gram-negative bacteria, and has a wide range of clinical indications.Clinical mainly used for sensitive bacteria caused by respiratory tract infection, urogenital system, cholecystitis, liver abscess, endocarditis, septicemia and soft tissue and ear infection.Due to its strong effect on escherichia coli, and most of the original drug from the kidney discharge, it is good for pyelonephritis and urinary tract infection.

 

Our strengths:
 
We can customize according to customer's requirement.
If you have any question pls mail us or call us.
 

 


 

Contact Details
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Phone Number : +86 18989305995

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