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Clear 98.0% Min 5 - Aza - 2 ' - Deoxycytidine CAS 2353-33-5 1.9g /cm3 Density

Basic Information
Place of Origin: CHINA
Brand Name: MOSINTER
Certification: COA
Model Number: Antineoplastic Drugs API - 6
Minimum Order Quantity: 1KG
Price: Negotiation
Packaging Details: Aluminum foil bag,kraft paper bag
Delivery Time: Within 7 days
Payment Terms: L/C, T/T
Supply Ability: Can be customized according to customer requirements
Detail Information
Name: 5 - Aza - 2 ' - Deoxycytidine CAS: 2353-33-5
Form: Powder Molecular Formula: C8H12N4O4
Molecular Weight: 228.21 Usage: Antineoplastic Drugs API
High Light:

pharmaceutical raw materials

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raw material for medicine manufacturing


Product Description

5 - Aza - 2 ' - deoxycytidine CAS 2353-33-5 Pharmaceutical Grade Chemicals

 

Description:

 

Appearance and properties : white crystalline powder

Density : 1.9g /cm3

Melting point : ~200 °C (dec.)

Boiling point : 485.8 ° C at 760 mmHg

Flash : DHS 247.6 C

Refractive index : 1.779

 

Specifications:

 

Item

Specification

Specific rotation

+39.5 to +41.5°

State of solution(transmittance)

Clear 98.0% min.

Chloride[cl]

0.020% max.

Ammonium [NH4]

0.02% max.

Sulfate[SO4]

0.020% max

Iron[Fe]

10ppm max.

Heavy metals [Pb]

10ppm max

Arsenic[As2O3]

1ppm max

Other amino acids

Chromatographically not detectable

Loss on drying

0.20% max.

Residue on ignition[sulfated]

0.10% max.

Assay

99.0% min

 

Application:

 

1. It is an epigenetic modification that inhibits the activity of DNA transmethylase, leading to gene activation in DNA demethylation (hypomethylation) and by remodeling "open" chromatin;When demethylation combined with histone acetylation, genes could be synergistically activated.5 '- nitrodeoxycytosine causes DNA demethylation or semi-demethylation;DNA demethylation regulates gene expression and improves nuclease sensitivity by "opening" chromatin to detectable structures that reshape chromatin structure and allow transcription factors to link gene promoter regions, transcription complex assembly, and gene expression

2. Descitabine has anti-tumor activity, which is manifested as a dual mechanism of dose difference.High concentration has cytotoxicity and low concentration has demethylation.It ACTS on proliferating (S) cells.

 

Our strengths:

 

We can customize according to customer's requirement.

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