Emtricitabine CAS 143491-57-0 C8H10FN3O3S Pharmaceutical Grade Chemicals

Basic Information
Place of Origin: CHINA
Brand Name: MOSINTER
Certification: COA
Model Number: Antibiotic Drugs API - 14
Minimum Order Quantity: 1KG
Price: Negotiation
Packaging Details: Aluminum foil bag , kraft paper bag
Delivery Time: Within 7 days
Payment Terms: L/C, T/T
Supply Ability: Can be customized according to customer requirements
Detail Information
Name: Emtricitabine CAS: 143491-57-0
Appearance: Powder Molecular Formula: C8H10FN3O3S
Molecular Weight: 247.25 Melting Point: 136-140°C
High Light:

pharmaceutical raw materials


raw material for medicine manufacturing

Product Description

Emtricitabine CAS 143491-57-0 C8H10FN3O3S Pharmaceutical Grade Chemicals


By the Gilead Siences company successfully developed a new type of nuclear nucleoside reverse transcriptase inhibitors, antiviral drugs, on HIV, HIV - 1-2 and has antiviral activity, HBV antiviral activity in its specificity to HIV - 1, 2 and HBV, HIV - and its drug concentration to mnol 100 / L, also did not see it on HSV - 1, 2, HCMV, VZV HSV -, corona, yellow fever virus, respiratory syncytial virus, Rota, or nasal influenza virus virus activity.Even lower than the molar concentration, the drug also showed the LAV and Ⅲ B strains of HIV 1 and HIV - 2 ROD2 and potent inhibition of ZY strains, the IC50 alue concentration is lower than AZT (zidovudine) 95 times.




Item Requirements Test Results
Description A white or almost white crystalline powder white crystalline powder

Freely soluble in Methanol and Water; Practically insoluble in



The infrared absorption spectrum is

concordant with the spectrum

obtained from Emtricitabine RS or

with the reference spectrum of



Limit of Emtricitabine


≤0.30% Not detected
Loss on Drying ≤0.5% (3 hours at 105°C) 0.14%
Residue on Ignition ≤0.1% Complies
  Total impurities ≤1.0% 0.10%
Residual Solvents Ethanol ≤0.30% 0.14%
  Dichloromethane ≤ 0.06% Not detected
  DMF ≤ 0.088% Not detected
  Triethylamine ≤ 0.032% Not detected
  Toluene NMT 0.089% Not detected
Heavy Metals ≤20ppm Complies
Assay 99.0% 99.0%
Conclusion Meets the Requirements




This product is a novel nucleoside reverse transcriptase inhibitor for HIV-

1. Both hiv-2 and HBV have antiviral activity.After oral administration, it is phosphorylated into the cell active 5 '-triphosphate, and 5' -triphosphate enters the viral DNA main chain and binds with the main chain, leading to the termination of the chain, thus inhibiting the activity of hiv-1 reverse transcriptase and HBV DNA polymerase.It is used in combination with other antiretrovirals for the treatment of adults with hiv-1 (AIDS) and hepatitis b.


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