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Emtricitabine CAS 143491-57-0 C8H10FN3O3S Pharmaceutical Grade Chemicals

Basic Information
Place of Origin: CHINA
Brand Name: MOSINTER
Certification: COA
Model Number: Antibiotic Drugs API - 14
Minimum Order Quantity: 1KG
Price: Negotiation
Packaging Details: Aluminum foil bag , kraft paper bag
Delivery Time: Within 7 days
Payment Terms: L/C, T/T
Supply Ability: Can be customized according to customer requirements
Detail Information
Name: Emtricitabine CAS: 143491-57-0
Appearance: Powder Molecular Formula: C8H10FN3O3S
Molecular Weight: 247.25 Melting Point: 136-140°C
High Light:

pharmaceutical raw materials

,

raw material for medicine manufacturing


Product Description

Emtricitabine CAS 143491-57-0 C8H10FN3O3S Pharmaceutical Grade Chemicals
 

Description:
 

By the Gilead Siences company successfully developed a new type of nuclear nucleoside reverse transcriptase inhibitors, antiviral drugs, on HIV, HIV - 1-2 and has antiviral activity, HBV antiviral activity in its specificity to HIV - 1, 2 and HBV, HIV - and its drug concentration to mnol 100 / L, also did not see it on HSV - 1, 2, HCMV, VZV HSV -, corona, yellow fever virus, respiratory syncytial virus, Rota, or nasal influenza virus virus activity.Even lower than the molar concentration, the drug also showed the LAV and Ⅲ B strains of HIV 1 and HIV - 2 ROD2 and potent inhibition of ZY strains, the IC50 alue concentration is lower than AZT (zidovudine) 95 times.

 

Specifications:

 

Item Requirements Test Results
Description A white or almost white crystalline powder white crystalline powder
Solubility

Freely soluble in Methanol and Water; Practically insoluble in

Dichloromethane

Complies
Identification

The infrared absorption spectrum is

concordant with the spectrum

obtained from Emtricitabine RS or

with the reference spectrum of

Emtricitabine

Complies

Limit of Emtricitabine

Enantiomer

≤0.30% Not detected
Loss on Drying ≤0.5% (3 hours at 105°C) 0.14%
Residue on Ignition ≤0.1% Complies
  Total impurities ≤1.0% 0.10%
Residual Solvents Ethanol ≤0.30% 0.14%
  Dichloromethane ≤ 0.06% Not detected
  DMF ≤ 0.088% Not detected
  Triethylamine ≤ 0.032% Not detected
  Toluene NMT 0.089% Not detected
Heavy Metals ≤20ppm Complies
Assay 99.0% 99.0%
Conclusion Meets the Requirements

 

Application:

 

This product is a novel nucleoside reverse transcriptase inhibitor for HIV-

1. Both hiv-2 and HBV have antiviral activity.After oral administration, it is phosphorylated into the cell active 5 '-triphosphate, and 5' -triphosphate enters the viral DNA main chain and binds with the main chain, leading to the termination of the chain, thus inhibiting the activity of hiv-1 reverse transcriptase and HBV DNA polymerase.It is used in combination with other antiretrovirals for the treatment of adults with hiv-1 (AIDS) and hepatitis b.

 

Our strengths:
 
We can customize according to customer's requirement.
If you have any question pls mail us or call us.
 

 

 

Contact Details
Fedor

Phone Number : +86 18989305995

WhatsApp : +18989305995