|Place of Origin:||CHINA|
|Minimum Order Quantity:||1KG|
|Packaging Details:||Aluminum foil bag, fiber can, kraft paper bag|
|Delivery Time:||Within 7 days|
|Supply Ability:||Can be customized according to customer requirements|
pharmaceutical fine chemicals,
industrial specialty chemicals
RIFAMYCIN SV CAS 6998-60-3 Industrial Fine Chemicals
The rifamycins are a group of antibiotics that are synthesized either naturally by the bacterium Amycolatopsis rifamycinica or artificially. They are a subclass of the larger family of ansamycins.
|Product name||Rifamycin S|
|Appearance||Yellow or orange yellow crystalline powder|
|Loss on drying||10.0%max|
1.Rifamycins have been used for the treatment of many diseases, the most important one being HIV-related tuberculosis. A systematic review of clinical trials on alternative regimens for prevention of active tuberculosis in HIV-negative individuals with latent TB found that a weekly, directly observed regimen of rifapentine with isoniazid for three months was as effective as a daily, self-administered regimen of isoniazid for nine months. But the rifapentine-isoniazid regimen had higher rates of treatment completion and lower rates of hepatotoxicity. However, the rate of treatment-limiting adverse events was higher in the rifapentine-isoniazid regimen.
2.The rifamycins have a unique mechanism of action, selectively inhibiting bacterial DNA-dependent RNA polymerase, and show no cross-resistance with other antibiotics in clinical use. However, despite their activity against bacteria resistant to other antibiotics, the rifamycins themselves suffer from a rather high frequency of resistance. Because of this, Rifampin and other rifamycins are typically used in combination with other antibacterial drugs.
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