High Purity Micro Fine Chemicals C37H47NO12 RIFAMYCIN SV CAS 6998-60-3

Basic Information
Place of Origin: CHINA
Brand Name: MOSINTER
Certification: COA
Model Number: Other-3
Minimum Order Quantity: 1KG
Price: Negotiation
Packaging Details: Aluminum foil bag, fiber can, kraft paper bag
Delivery Time: Within 7 days
Supply Ability: Can be customized according to customer requirements
Detail Information
Name: RIFAMYCIN SV CAS: 6998-60-3
Appearance: Powder Molecular Formula: C37H47NO12
Molecular Weight: 697.77 Purity: 96%
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Product Description

RIFAMYCIN SV CAS 6998-60-3 Industrial Fine Chemicals



The rifamycins are a group of antibiotics that are synthesized either naturally by the bacterium Amycolatopsis rifamycinica or artificially. They are a subclass of the larger family of ansamycins.




Items Technical index
Product name Rifamycin S
Synonyms 1,4-Dideoxy-1,4-dihydro-1,4-dioxo-rifamycin
Molecular Formula C37H45NO12
CAS No 13553-79-2
Molecular Weight 695.15
Appearance Yellow or orange yellow crystalline powder
Assay 96%min
Loss on drying 10.0%max
Sulphated ash 0.5%max
Related substances 2.0%max



1.Rifamycins have been used for the treatment of many diseases, the most important one being HIV-related tuberculosis. A systematic review of clinical trials on alternative regimens for prevention of active tuberculosis in HIV-negative individuals with latent TB found that a weekly, directly observed regimen of rifapentine with isoniazid for three months was as effective as a daily, self-administered regimen of isoniazid for nine months. But the rifapentine-isoniazid regimen had higher rates of treatment completion and lower rates of hepatotoxicity. However, the rate of treatment-limiting adverse events was higher in the rifapentine-isoniazid regimen.

2.The rifamycins have a unique mechanism of action, selectively inhibiting bacterial DNA-dependent RNA polymerase, and show no cross-resistance with other antibiotics in clinical use. However, despite their activity against bacteria resistant to other antibiotics, the rifamycins themselves suffer from a rather high frequency of resistance. Because of this, Rifampin and other rifamycins are typically used in combination with other antibacterial drugs.


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