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Naproxen sodium CAS 26159-34-2 C14H13NaO3 Pharmaceutical Grade Chemicals

Basic Information
Place of Origin: CHINA
Brand Name: MOSINTER
Certification: COA
Model Number: Antibiotic Drugs API - 11
Minimum Order Quantity: 1KG
Price: Negotiation
Packaging Details: Aluminum foil bag , kraft paper bag
Delivery Time: Within 7 days
Payment Terms: L/C, T/T
Supply Ability: Can be customized according to customer requirements
Detail Information
Name: Naproxen Sodium CAS: 26159-34-2
Appearance: Powder Molecular Formula: C14H13NaO3
Molecular Weight: 252.24 Melting Point: 250-251°C
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pharmaceutical raw materials

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raw material for medicine manufacturing


Product Description

Naproxen sodium CAS 26159-34-2 C14H13NaO3 Pharmaceutical Grade Chemicals
 
Description:
 

White or white crystalline powder;Odourless;Slightly hygroscopic.

It is soluble in water, methanol, ethanol and acetone.Is almost insoluble in chloroform or toluene.

For specific curl, 0.5g of the product was taken, 6ml of water was added, and 2.4ml of 1mol/L hydrochloric acid solution was added, and the product was shaken at the same time. After precipitation, the product was washed with neutral water, dried at 105℃ to constant weight, and accurately weighed. The solution containing 10mg per 1ml was made by adding chloroform.In accordance with the measurement (appendix Ⅵ E) curl is + 63 ° to + 69 °.

 

Specifications:

 

Appearance White to almost white crystalline powder Almost white crystalline
Loss on drying ≤1.0% 0.2%
Heavy metals ≤0.002% <0.002%
Related substances (HPLC) Impurity D(in-house) ≤0.10% <0.01%
Impurity E(in-house, Impurity C in EP) ≤0.10% <0.01%
Any other impurity ≤0.10% <0.01%
Total impurities ≤0.5% <0.01%
Residual Solvents Toluene ≤50ppm <1ppm
Methanol ≤50ppm <12ppm
Ethanol ≤100ppm <8ppm

[Assay] (On the dried basis)

It contains C14H13NaO3

98.5% to 101.5% 99.7%

 

Application:
 
Suitable for relieving all kinds of mild to moderate pain, such as tooth extraction and other postoperative pain, primary dysmenorrhea and headache, etc.It is applicable to rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, Juvenilearthritis, tendinitis, bursitis, and acute gout arthritis, relieving pain, swelling, and limited activity of arthritis.Compared with aspirin and indomethacin, the effect of symptom relief was similar, but the incidence and severity of gastrointestinal and neurological adverse reactions were lower.
 
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