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Pimecrolimus CAS 137071-32-0 ASM 981 SDZ-ASM 981,Pharmaceutical Grade Chemicals

Basic Information
Place of Origin: CHINA
Brand Name: MOSINTER
Certification: COA
Model Number: Other Pharmaceutical API-2
Minimum Order Quantity: 1KG
Price: Negotiation
Packaging Details: Aluminum foil bag , kraft paper bag
Delivery Time: Within 7 days
Payment Terms: L/C, T/T
Supply Ability: Can be customized according to customer requirements
Detail Information
Name: Pimecrolimus CAS: 137071-32-0
Form: Powder Molecular Formula: C43H68ClNO11
Molecular Weight: 810.459 Package: Aluminium Foil Bag
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Product Description

Pimecrolimus CAS 137071-32-0 ASM 981 SDZ-ASM 981,Pharmaceutical Grade Chemicals
 

Description:

 

Pimecrolimus is a topical immunomodulators and is a kind of semi-synthetic products of the Streptomyces-produced ascomycin. It has a greater lipophilicity than tacrolimus with a stronger affinity with the skin. It can effectively and safely control the signs and symptoms of facial seborrheic dermatitis and can quickly relieve the itching symptoms of patients with dermatitis and eczema as well as reduce the lesion area, clear atopic dermatitis (eczema) sign. Therefore, it is an effective treatment method for the treatment of atopic dermatitis (eczema) for both early remission purpose and long-term control purpose.

 

Specifications:
 

Name: Pimecrolimus
CAS: 137071-32-0
Molecular Formula: C43H68ClNO11
Molecular Weight: 810.459
Brand: MOSINTER
Content: 98%min
Synonyms 1: ASM 981
Synonyms 2: SDZ-ASM 981
storage temp: -20°C
density: 1.19

 

Application: 

 

1) Macrolactam ascomycin derivative; inhibits production of pro-inflammatory cytokines by T cells and mast cells. Immunosuppresant.
2) Pimecrolimus caused a strong and dose-dependent inhibition of anti-IgE–induced release of histamine from mast cells and basophils (maximally 73% and 82%, respectively, at 500 nmol/L pimecrolimus) and of mast cell tryptase (maximally 75%) and a less pronou.


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