|Place of Origin:||CHINA|
|Model Number:||Other Pharmaceutical API-2|
|Minimum Order Quantity:||1KG|
|Packaging Details:||Aluminum foil bag , kraft paper bag|
|Delivery Time:||Within 7 days|
|Payment Terms:||L/C, T/T|
|Supply Ability:||Can be customized according to customer requirements|
|Molecular Weight:||810.459||Package:||Aluminium Foil Bag|
chemical raw materials,
pharmaceutical raw materials
Pimecrolimus CAS 137071-32-0 ASM 981 SDZ-ASM 981,Pharmaceutical Grade Chemicals
Pimecrolimus is a topical immunomodulators and is a kind of semi-synthetic products of the Streptomyces-produced ascomycin. It has a greater lipophilicity than tacrolimus with a stronger affinity with the skin. It can effectively and safely control the signs and symptoms of facial seborrheic dermatitis and can quickly relieve the itching symptoms of patients with dermatitis and eczema as well as reduce the lesion area, clear atopic dermatitis (eczema) sign. Therefore, it is an effective treatment method for the treatment of atopic dermatitis (eczema) for both early remission purpose and long-term control purpose.
|Synonyms 1:||ASM 981|
|Synonyms 2:||SDZ-ASM 981|
1) Macrolactam ascomycin derivative; inhibits production of pro-inflammatory cytokines by T cells and mast cells. Immunosuppresant.
2) Pimecrolimus caused a strong and dose-dependent inhibition of anti-IgE–induced release of histamine from mast cells and basophils (maximally 73% and 82%, respectively, at 500 nmol/L pimecrolimus) and of mast cell tryptase (maximally 75%) and a less pronou.
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