|Place of Origin:||CHINA|
|Model Number:||Antineoplastic Drugs API - 17|
|Minimum Order Quantity:||1KG|
|Packaging Details:||Aluminum foil bag,kraft paper bag|
|Delivery Time:||Within 7 days|
|Payment Terms:||L/C, T/T|
|Supply Ability:||Can be customized according to customer requirements|
|Name:||PeMetrexed DisodiuM 7-hydrate||CAS:||357166-29-1|
|Molecular Weight:||597||Usage:||Antineoplastic Drugs API|
pharmaceutical raw materials,
raw material for medicine manufacturing
PeMetrexed disodiuM 7-hydrate CAS 357166-29-1 Pharmaceutical Grade Chemicals
Pemetrexed is chemically similar to folic acid and is in the class of chemotherapy medicine called folate antimetabolites. It works by inhibiting three enzymes used in purine and pyrimidine synthesis—thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT). By inhibiting the formation of precursor purine and pyrimidine nucleotides, pemetrexed prevents the formation of DNA and RNA, which are required for the growth and survival of both normal cells and cancer cells.
Almost-white powder, smell-less, hygroscopic freely.
white powder, smell-less, hygroscopic freely.
Soluble in water very freely, hardly soluble in ethanol or chloroform or ethyl ether.
Specific optical rotation
(1)The product appears flame reaction of sodium salt.
Clarity and color of solution
Meet the requirements.
Max single impurity≤0.1%
An organic sodium salt that is the heptahydrate form of pemetrexed disodium. Inhibits thymidylate synthase (TS), 421 dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT).
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