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Sulfasalazine CAS 599-79-1 Salazosulfapyridine Pharmaceutical Grade Chemicals

Basic Information
Place of Origin: CHINA
Brand Name: MOSINTER
Certification: COA
Model Number: Antibiotic Drugs API - 42
Minimum Order Quantity: 1KG
Price: Negotiation
Packaging Details: Aluminum foil bag , kraft paper bag
Delivery Time: Within 7 days
Payment Terms: L/C, T/T
Supply Ability: Can be customized according to customer requirements
Detail Information
Name: Sulfasalazine CAS: 599-79-1
Form: Powder Molecular Formula: C18H14N4O5S
Molecular Weight: 398.4 Flashing Point: 260-265 °C (dec.)(lit.)
High Light:

chemical raw materials

,

raw material for medicine manufacturing


Product Description

Sulfasalazine CAS 599-79-1 Salazosulfapyridine Pharmaceutical Grade Chemicals
 
Description:
 
This product is sulfonamide antibacterial drug.It is an oral sulfa drug that is difficult to be absorbed. The absorbed part is decomposed into 5-aminosalicylic acid and sulfa pyridine under the action of intestinal microorganisms.After complexation with intestinal wall connective tissue, 5-aminosalicylic acid stays in intestinal wall tissue for a long time and plays an antibacterial, anti-inflammatory and immunosuppressive role, such as reducing escherichia coli and clostridium difficile, and inhibiting the synthesis of prostaglandins and other inflammatory mediators, leukotrienes.Therefore, 5-aminosalicylic acid (5-aminosalicylic acid) is considered to be the main component of this product to produce curative effect on inflammatory bowel disease.The sulfapyridine produced by the decomposition of this product has a weak antibacterial effect on intestinal flora.
 
Specifications:

 

Tests

Specifications

Test results

Appearance

Bright yellow or brownish-

Brownish-yellow,fine powder

yellow,fine powder

Solubility

Very slightly soluble in alcohol,

Conform

practically insoluble in water,in

ether,in chloroform,and in

benzene,soluble in aqueous

solutions of alkali hydroxides

Melting point

About 255°C

261.0°C

Loss on drying

≤1.0%

0.24%

Residue on ignition

≤0.5%

0.20%

Chloride

≤0.014%

<0.014%

Sulfate

≤0.04%

<0.04%

Heavy metals

≤0.002%

<0.002%

Chromatographic

Individual

≤2.0%

<2.0%

purity

impurity

 

Total

≤4.0%

<4.0%

 

impurities

Assay

97.0% ~ 101.5%

99.90%

Conclusion: The Product complies with USP 35 standard.


Application: 
 

 For the treatment of ulcerative colitis.The product is rarely absorbed after oral administration and plays a therapeutic role in intestinal wall decomposition.Anti - inflammatory and anti - bacterial.In recent years, many data show that it can also inhibit the synthesis of immune complex and rheumatoid factors, thus affecting the immunopathological damage of rheumatoid arthritis.The drug has been used to treat inflammatory bowel disease and rheumatoid arthritis for more than 40 years.Due to the short-term and non-controlled application of sulfamyridine in the past, the efficacy of sulfamyridine has been controversial.Trials in the late 1970s showed that the drug improved clinical symptoms of rheumatoid arthritis and reduced c-reactive protein and erythrocyte sedimentation rate to varying degrees


Our strengths:
 
We can customize according to customer's requirement.
If you have any question pls mail us or call us.
 

 


 

Contact Details
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