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Vancomycin CAS 1404-90-6 C66H75Cl2N9O24 Pharmaceutical Grade Chemicals

Basic Information
Place of Origin: CHINA
Brand Name: MOSINTER
Certification: COA
Model Number: Antibiotic Drugs API - 37
Minimum Order Quantity: 1KG
Price: Negotiation
Packaging Details: Aluminum foil bag , kraft paper bag
Delivery Time: Within 7 days
Payment Terms: L/C, T/T
Supply Ability: Can be customized according to customer requirements
Detail Information
Name: Vancomycin CAS: 1404-90-6
Form: Powder Molecular Formula: C66H75Cl2N9O24
Molecular Weight: 1449.25 Density: 1.65 G/cm3
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Product Description

Vancomycin CAS 1404-90-6 C66H75Cl2N9O24 Pharmaceutical Grade Chemicals
 
Description:

 

Vancomycin is a branched tricyclic glycosylated nonribosomal peptide produced by the Actinobacteria species Amycolatopsis orientalis (formerly designated Nocardia orientalis).

Vancomycin exhibits atropisomerism — it has multiple chemically distinct rotamers owing to the rotational restriction of some of the bonds. The form present in the drug is the thermodynamically more stable conformer, so has more potent activity.

 

Specifications:

 

Item

Requirements

Results

Appearance

A white or almost white powder

An almost white powder

Identification

The retention time of the principal peak in the chromatogram obtained with test solution(a) is similar to the reference solution , comples

Complies

Reaction (a) of chlorides ,complies

Complies

Appearance of solution

Clear

Clear

Water

≤5.0%

1.9%

Ph

2.5~4.5

2.9

Limit of monodechlorovancomycin

≤4.7%

2.1%

Sulphated ash

≤1.0%

0.2%

Assay(microbial)(anhydrous basis)

≥900 μg/mg

1035 μg/mg

Bacterial endotoxins

≤ 0.33EU/mg

Complies

Sterility

Sterility

Sterility

Heavy metals

≤30ppm

<30ppm

Composition of Cancomycin

Vancomycin B:≥ 85.0%

Any peak other than the main peak:≤5.0%

94.3%

1.5%

 

Application: 

 

1. Kill bacteria by inhibiting their growth and reproduction.The drug interferes with cell wall synthesis by interfering with peptidoglycan, a key component of bacterial cell wall structure, inhibiting the production of phospholipids and peptides in cell walls.

2. Vancomycin is mainly used in the treatment of infection in four aspects: firstly, the treatment of drug-resistant bacterial infection;It is also used in the treatment of pseudomembranous enteritis caused by clostridium difficile.

3. Vancomycin can also be used to treat colitis and intestinal inflammation;Vancomycin is also often used to prevent infection with devices such as cardiac catheters and intravenous catheters.Vancomycin can be used alone or in combination.

4. can inhibit the synthesis of bacterial cell wall, staphylococcus aureus, streptococcus pyogenes, streptococcus pneumoniae and other effects, difficult to distinguish bacillus, bacillus anthracis, diphtheria bacteria and other effects are good.

5. No cross-resistance with other antibiotics, and few drug-resistant strains.Mainly used for endocarditis, septicemia, pseudomembranous enteritis, etc.

6. If the drug is not absorbed by oral administration, it must be dissolved with water for injection and the infusion time shall not be less than 1 hour.Rapid drip skin reaction, too high concentration can cause thrombophlebitis;Muscle injection can cause severe pain, so not muscle injection;It has severe ototoxicity and renal toxicity, so it should only be used for short-term rescue.

 

Our strengths:
 
We can customize according to customer's requirement.
If you have any question pls mail us or call us.
 

 

 

 

 

Contact Details
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Phone Number : +86 18989305995

WhatsApp : +18989305995